The follow-up, in public

We come back. At month one, month four, and month twelve.

Every Cases patient is followed up on a fixed schedule, with the same panel re-run, the protocol re-evaluated, and the result published. We publish the cases that worked. We publish the cases that didn't. Both are useful.

Pre-committed Follow-up windows are set before the protocol begins.
Published either way Non-improving cases air with the same care as successes.
Why it matters

Without follow-up, there is no clinical knowledge.

The most common reason health advice fails to compound is that no one closes the loop. A clinician recommends, a patient tries, and what actually happened — over weeks, over months, over a year — disappears.

We close the loop in public. Each protocol pre-commits to the markers we will re-check and the windows we will check them in. The follow-up episode walks through the new labs with the same care as the first. If the protocol is working, we say so. If a marker is moving in the wrong direction, we say so. If we were wrong, we say that too — and we say what we'd do differently knowing what we know now.


Example arc · 01

A case that's working.

The endurance-runner case from the protocol library. Twelve months on a single page. (Illustrative — not a specific real patient.)

Subjective energy & key markers, over twelve months

Baseline
"Tired all the time." Reference
Month 1
Mornings better + early signal
Month 4
Training quality up + decisive
Month 12
Sustained + holding

Ferritin (ng/mL) · iron storage

Ferritin over time Ferritin rises from 22 ng/mL at baseline to 84 ng/mL at month twelve, moving into the optimal 50 to 150 ng/mL range by month four. Optimal range 50–150 150 50 0 Baseline 22 Month 1 38 Month 4 71 Month 12 84
Patient value Optimal range band

Free T3 (pg/mL) · active thyroid hormone

Free T3 over time Free T3 rises from 2.6 pg/mL at baseline to 3.7 pg/mL at month twelve, moving into the 3.2 to 4.2 pg/mL optimal range. Optimal range 3.2–4.2 4.5 3.0 1.5 Baseline 2.6 Month 1 2.7 Month 4 3.3 Month 12 3.7
Patient value Optimal range band
"The most important number on this page is the one at month one. Ferritin moved on schedule — which meant the protocol was probably right, and we could leave the rest of it alone for three more months."
— Cases follow-up note, M1

Example arc · 02

A case that didn't go as planned.

The harder, more useful kind of episode. The protocol's first hypothesis was wrong; the follow-up is what got the patient to the actual answer.

The story

A 38-year-old with persistent low-grade GI symptoms and stubborn anemia. The first protocol treated the anemia in the simplest way — oral iron, with a clear plan to re-check ferritin at month one and the full panel at month four.

At month one, ferritin had barely moved despite excellent adherence. That single result re-opened the differential. The next round of workup found the actual upstream cause, the protocol was rewritten, and by month twelve the picture was substantially different. The first protocol stays published — with what we learned from it attached.

No real patient details. The pattern is real; the case is illustrative.

Ferritin, with a non-response signal at month 1

Optimal 50–150 Non-response · protocol revised Baseline 18 Month 1 21 Month 4 64 Month 12 78
Patient value Non-response signal Optimal range band

How the first protocol was revised

The standing rule

We don't hide the cases that didn't work. Those are often the episodes worth watching most.

The point of a longitudinal record isn't to flatter the doctor. It's to make medicine learn faster — out loud, in front of the people it's meant to serve.